產(chǎn)品編號 yb-0720M
英文名稱 Anti-AD7C-NTP抗體
中文名稱 神經(jīng)絲蛋白抗體
別    名 neuronal thread protein AD7c-NTP; AD7c-NTP.
Anti-AD7C-NTP抗體  
說 明 書 0.2ml  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  
抗體來源 Mouse
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AD7C-NTP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease.

Database links:
GenBank: AAC08737.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

是存在于神經(jīng)元中的一種41Kda的蛋白質(zhì)，在AD患者腦內(nèi)選擇性升高，和其病理過程相關(guān)，AD7C-NTP基因也只在神經(jīng)元表達(dá)，AD患者腦脊液中AD7C-NTP表達(dá)升高， AD7C-NTP作為AD早期診斷和確診的生物化學(xué)標(biāo)志正引起越來越多的關(guān)注.