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產(chǎn)品分類 / PRODUCT

Anti-ADCY2抗體
描述:

Anti-ADCY2抗體β抑制因子-2又稱β休止蛋白2,也是是調(diào)節(jié)CD4+T細胞存活和自身免疫性的關(guān)鍵因子,與促進T淋巴細胞存活和自身免疫發(fā)病相關(guān)。經(jīng)研究發(fā)現(xiàn)β-arrestin不僅僅能阻斷蛋白合成,也能誘導(dǎo)蛋白合成,參與信號傳導(dǎo)。

  • 產(chǎn)品型號:
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時間:2025-12-10
  • 訪問量:135
產(chǎn)品介紹/ PRODUCT PRESENTATION

產(chǎn)品編號 yb-3920R
英文名稱 Anti-ADCY2抗體
中文名稱 腺苷酸環(huán)化酶2抗體
別    名 adenylate cyclase 2; HBAC2; KIAA1060; type II adenylate cyclase; ADCY2_HUMAN.
 Anti-ADCY2抗體  
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  生長因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADCY2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
PubMed PubMed
產(chǎn)品介紹 background:
ADCY2 is a membrane-bound, calmodulin-insensitive adenylyl cyclase.

Function:
This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. 

Subunit:
Interacts with RAF1. 

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in brain.

Post-translational modifications:
Phosphorylated by RAF1.

Similarity:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. 
Contains 2 guanylate cyclase domains.

Database links:
UniProtKB/Swiss-Prot: Q08462.5

 Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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