產(chǎn)品編號(hào) yb-7046R
英文名稱 Anti-ANGPTL5抗體
中文名稱 血管生成素相關(guān)蛋白5
別    名 Angiopoietin like 5; Angiopoietin related protein 5; Angiopoietin-like protein 5; Angiopoietin-related protein 5; ANGL5_HUMAN; ANGPTL 5; ANGPTL5; Fibrinogen like; hide
Anti-ANGPTL5抗體
說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 心血管  生長(zhǎng)因子和激素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Chicken, Pig, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANGPTL5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Angptl5 (angiopoietin-like 5) is a 388 amino acid secreted protein that contains one fibrinogen C-terminal domain and is primarily expressed in adult heart tissue. The gene encoding Angptl5 maps to human chromosome 11. With approximay 135 million base pairs and 1,400 genes, chromosome 11 comprises approximay 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-angiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Subcellular Location:
Secreted (Potential). 

Tissue Specificity:
Mainly expressed in adult heart.

Similarity:
Contains 1 fibrinogen C-terminal domain.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.