產(chǎn)品編號 yb-9101R
英文名稱 Anti-ARSH抗體
中文名稱 芳香基硫酸酯酶H抗體
別    名 Arylsulfatase H; ASH; ARSH_HUMAN.
Anti-ARSH抗體   
說 明 書 0.2ml  
研究領域 心血管  細胞生物  免疫學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARSH
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling and degradation of macromolecules. Arylsulfatase H, also known as ARSH, is a 562 amino acid protein that belongs to the sulfatase family of bone and cartilage matrix proteins. Localized to the plasma membrane, Arylsulfatase H uses calcium as a cofactor to hydrolyze sulfate esters. The gene encoding Arylsulfatase D maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential). 

Post-translational modifications:
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity). 

Similarity:
Belongs to the sulfatase family. 


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.