產(chǎn)品編號yb-6586R
英文名稱 Anti-FCAR/CD89抗體
中文名稱 免疫球蛋白A Fc段受體1抗體
別    名 CD89; Fc alpha receptor; FCAR; FCAR_HUMAN; IgA Fc receptor; Immunoglobulin alpha Fc receptor.
Anti-FCAR/CD89抗體    
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 免疫學(xué)  細(xì)胞表面分子  細(xì)胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
細(xì)胞定位 細(xì)胞膜 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FCAR
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
Tissue specificity; Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.

Subunit:
Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2.

Subcellular Location:
Isoform A.1: Cell membrane; Single-pass type I membrane protein. 
Isoform A.2: Cell membrane; Single-pass type I membrane protein.
Isoform A.3: Cell membrane; Single-pass type I membrane protein.
Isoform B: Secreted.
Isoform B-delta-S2: Secreted.

Tissue Specificity:
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.