產(chǎn)品編號 yb-6861R
英文名稱Anti-FEM1A抗體
中文名稱 前列腺素E受體4相關(guān)蛋白抗體
別    名 EPRAP; Fem-1 homolog a (C. elegans); Fem1 homolog a; FEM1-alpha-A; FEM1a-A; Fem1aa; Feminization 1 homolog a (C. elegans); Feminization 1 homolog a; Prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; Protein fem-1 homolog A-A; FEM1A_HUMAN.
Anti-FEM1A抗體
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FEM1A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
FEM1A is a caspase substrate homologous to the C. Elegans sex determining protein, FEM-1. Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4. Overexpression of FEM1A in mammalian cells is reported to induce apoptosis.

Function:
Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4.

Subunit:
Component of some E3 ubiquitin-protein ligase complex. Interacts with PTGER4.

Subcellular Location:
Cytoplasm (Probable).

Tissue Specificity:
Present in macrophages derived from peripheral blood monocytes. Also present in atheromata (at protein level).