產(chǎn)品編號 yb-5133R
英文名稱 Anti-ALDH1B1抗體
中文名稱 乙醛脫氫酶5抗體
別    名 Aldehyde dehydrogenase 5; Acetaldehyde dehydrogenase 5; Aldehyde dehydrogenase 1B1; Aldehyde dehydrogenase family 1 member B1; Aldehyde dehydrogenase X mitochondrial; ALDH class 2; ALDH1B1; ALDH5; ALDHX; AL1B1_HUMAN; MGC2230; Mitochondrial aldehyde dehydrogenase X; OTTHUMP00000021399.
Anti-ALDH1B1抗體
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 免疫學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
細胞定位 細胞漿 線粒體
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ALDH1B1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
ALDH1B1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. The ALDH1B1 gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.

Function:
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.

Subunit:
Homotetramer.

Subcellular Location:
Mitochondrion matrix.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.