產(chǎn)品編號(hào) yb-5139R
英文名稱 Anti-ALF抗體
中文名稱 通用轉(zhuǎn)錄因子IIA樣因子抗體
別    名 General transcription factor II A 1 like factor; GTF2A1LF; SALF; Stonin 1; TFIIA alpha and beta like factor; TF2AY_HUMAN; 1-like factor; General transcription factor II A; Gtf2a1l; TFIIA-alpha and beta-like factor.
Anti-ALF抗體
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ALF
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involves the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. ALF is a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.

Function:
May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.

Subcellular Location:
Nucleus.

Tissue Specificity:
Testis specific.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

通用轉(zhuǎn)錄因子IIA樣因子抗體又稱TFIIAα/β樣因子抗體。